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pentobarbital will reduce the extent or influence of fesoterodine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.pentobarbital will lower the extent or outcome of estropipate by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.pentobarbital will reduce the level or effect of amlodipine by a